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"The Vital Role of Coenzyme Q10: Benefits, Needs, and Who Should Supplement"
Coenzyme Q10 generally has two raw materials for the production of health products: one is the common oxidized Coenzyme Q10, English is Ubiquinone, and the other is the reduced Coenzyme Q10, English is Ubiquinol.
The main role of Coenzyme Q10 in the human body:
Coenzyme Q10 is involved in energy production in mitochondria. Mitochondria are the energy factories of the cell, producing adenosine triphosphate (ATP) by oxidizing substances such as sugars, fats and amino acids to power the cell. You can think of ATP as a kind of battery that provides energy to the cell. When ATP is used, it becomes ADP, just like when a battery runs out. Coenzyme Q10 acts as a kind of charger, it helps ADP to turn back into ATP, just like a battery is full. In this way, the cell can once again use ATP for various life activities. Therefore, Coenzyme Q10 is very important for maintaining cellular energy levels and normal metabolism, especially in tissues and organs with high energy requirements, such as the heart, liver, kidneys, muscles, and brain.
Who needs a coQ10 supplement?
⚪Old people
The first is the elderly, because as we age, we need more antioxidants. The body's own ability to synthesize Coenzyme Q10 reaches its peak at about 20 years old, and then gradually declines with age, especially in high-energy-consuming organs such as the heart, where the concentration of Coenzyme Q10 will be significantly reduced. A 70-year-old is younger than a 20-year-old. Coenzyme Q10 can be reduced by more than 50%, which is why many elderly people need to supplement Coenzyme Q10, if long-term supplementation will have a feeling of energy recovery.
⚪Patients with cardiovascular and cerebrovascular diseases
Cardiovascular and cerebrovascular diseases are related to oxidative stress and energy metabolism disorders, such as coronary heart disease, heart failure, hypertension, atherosclerosis, stroke, etc. Patients with these diseases are often accompanied by low Coenzyme Q10 levels, which may lead to myocardial ischemia, decreased myocardial contractility, arrhythmia, cardiomyocyte apoptosis, etc. Supplementation of Coenzyme Q10 can improve cardiac function, reduce blood pressure, reduce myocardial ischemia and hypoxia damage, prevent or delay the progression of atherosclerosis, and protect neurons from ischemic injury. Multiple clinical trials and analyses have confirmed the benefits of Coenzyme Q10 for patients with cardiovascular and cerebrovascular diseases, especially for those taking statins, which inhibit Coenzyme Q10 synthesis and cause side effects such as muscle pain, myitis and rhabdomyolysis. (The nocebo effect is more likely to occur in people who are familiar with the side effects of statins.)
⚪Patients with metabolic diseases
Metabolic disease is a disease related to abnormal energy metabolism, such as diabetes, obesity, hyperlipidemia, etc. Patients with these diseases are often accompanied by low Coenzyme Q10 levels, which may lead to mitochondrial dysfunction, insulin resistance, fatty liver, arteriosclerosis, etc. Supplementation of Coenzyme Q10 can improve insulin sensitivity, reduce blood sugar and blood lipids, reduce oxidative stress in adipose tissue, and prevent or improve non-alcoholic fatty liver disease. Several clinical trial analyses have shown the benefit of Coenzyme Q10 in patients with metabolic diseases, especially those taking hypoglycemic or lipid-lowering drugs, as these drugs can also affect the synthesis or utilization of Coenzyme Q10.
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