With the progress of extraction technology, the bioactive substance of milk thistle was determined to be Silymarin.

Silymarin is the general name of a large class of flavonoid lignans, the main pharmacological effects are (Silibinin), (Isosilibinin), (silichristin) and (Silidianin), the proportion of 3:1:1:1. The content and activity of Silibinin were the highest.

⚪Pharmacological studies have shown that Silymarin has obvious repair and protection effects on hepatocytes, and its main mechanism of action is as follows Silymarin has obvious protective effect on hepatocytes and can effectively reduce the damage of toxic substances to hepatocytes.

Studies have shown that silymarin can bind to the cell membrane of hepatocytes, maintain the fluidity of the cell membrane through anti-lipid peroxidation, reduce the attack of toxic substances on the liver cell membrane, interrupt its transmembrane transport and intercellular transmission, so as to effectively enhance the resistance of hepatocytes to various toxic substances and effectively protect the integrity of hepatocytes.

⚪Silymarin has obvious anti-fibrosis effect, can effectively inhibit liver sclerosis, and retain normal liver function. 

Studies have shown that silymarin has obvious anti-inflammatory and antioxidant stress activities, which can effectively regulate the synthesis and degradation of extracellular matrix components, inhibit the activation of inflammatory factors for the fibrosis process, thereby reducing the conversion of fibrinogen to fibrin, alleviating liver fibrosis, and preserving the normal structure and function of liver.

⚪Silymarin can effectively promote the repair and regeneration of liver cells, thus restoring the normal function of the liver. 

Studies have shown that silymarin can bind to the estradiol receptor on the surface of liver cells, through and activate the estradiol receptor, thus enhancing the activity of RNA polymerase I in the liver nucleus, promoting the synthesis of various substances such as DNA and RNA in liver cells, and promoting the synthesis of various biological enzymes and structural proteins in cells, so as to effectively promote the regeneration and repair of liver cells. To restore the normal function of damaged liver cells.

⚪Silymarin has certain inhibitory effect on hepatitis C virus.

HCV is one of the common clinical viral hepatitis, which is mainly transmitted through blood. The research results show that silymarin can inhibit the activity of the polymerase by competitively binding the active region of the non-structural region of the virus gene, thus interfering with the auxiliary of HCV and playing a certain antiviral role.

As one of the main products of LongYoung Health Company, Silymarin has won the trust of customers at home and abroad with high quality supply chain management and competitive prices. Our company's Silymarin is exported to Europe, North America, Australia, Japan and South Korea and other countries and regions.

Company Email：admin@longyounghealth.com